Native plants such as coastal redwood and giant sequoia are affected by this pathogen which causes tip dieback and death of moderate sized branches and the trunk. Botryosphaeria species can also infect the fruit of woody plants such as almond, pistachio, avocado, grape, and apple.
Botryosphaeria canker diseases cause symptoms when the pathogen kills the sapwood of a branch, cutting off water flow to the leaves. The first indication of a Botryosphaeria disease is yellowing (or chlorosis) of leaves on a single branch while other branches appear normal. As the fungus girdles the last sections of living tissue, symptoms of yellowed and necrotic or dead leaves, wilting, or excessive leaf drop usually occur. Chlorotic leaves drop from infected branches, resulting in deadwood in the canopy
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